primary

von Moltke J, O’Leary CE, Barrett NA, Kanaoka Y, Austen F, Locksley RM (2017). Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med 214(1):27-37. PDF

von Moltke J, Ji M, Liang H-E, Locksley RM (2016). Tuft cell-derived IL-25 regulates an intestinal ILC2 – epithelial response circuit. Nature 529:221-5. PDF

von Moltke J and Locksley RM (2014). I-L-C-2 it: type 2 immunity and group 2 innate lymphoid cells in homeostasis. Current Opinions in Immunology 31:58-65. PDF

von Moltke J, Ayres JS, Kofoed EM, Chavarría-Smith J, Vance RE (2012) Recognition of Bacteria by Inflammasomes. Annu Rev Immunol 31:73-106. PDF

von Moltke J, Moayeri M, Trinidad NJ, Kintzer AF, Wang SB, van Rooijen N, Krantz BA, Leppla SH, Gronert K, Vance RE. (2012) Rapid induction of inflammatory lipid mediators by the inflammasome in vivoNature 490: 107-11. PDF

Broz P*, von Moltke J*, Jones JW, Vance RE, Monack DM (2010) Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe 8: 471-483. PDF

 

collaborations

Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE (2017). NAIP-NLRC4 inflammasomes coordinate intestinal epithelial cell expulsion with eicosanoid and IL-18 release via activation of Caspase-1 and -8. Immunity 46(4):649-59. PDF

Nussbaum JC, Van Dyken SJ, von Moltke J, Cheng LE, Mohapatra A, Molofsky AB, Thornton EE, Krummel MF, Chawla A, Liang H-E, Locksley RM (2013) Type II innate lymphoid cells control eosinophil homeostasis. Nature 502:245-248. PDF

Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, et al. (2011) The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect Immun 79: 688-694. PDF

Lightfield KL, Persson J, Brubaker SW, Witte CE, von Moltke J, et al. (2008) Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol 9: 1171-1178. PDF

Quinzii CM, Lopez LC, von Moltke J, Naini A, Krishna S, et al. (2008) Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency. FASEB J 22: 1874-1885.

 

* These authors contributed equally to this work.